Are You Insulin Resistant? How to Know and What to Do

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Special Thanks to my team and Nicholas Norwitz - Oxford Ketone PhD Researcher and Harvard Med Student - for working diligently on research as well!

Are You Insulin Resistant? How to Know and What to Do - Thomas DeLauer

There's some very telltale signs that you could be insulin resistant. The scary thing with insulin resistance is that so many people walk around not even knowing that they're insulin resistant. When I was a hundred pounds overweight, I didn't know that I was insulin resistant. I didn't know that I was prediabetic until I actually looked at blood work.

But now in retrospect, I look back at the signs, I realize, "Hey, I had a lot of these symptoms." So I wanted to lay them out for you. I also wanted to explain what insulin resistance is in a simple nutshell. So we're going to dive all into this and you're going to have a clear understanding of whether you're insulin resistant or not. Or maybe you can start pinpointing people in your life that could be so you can help them get some help.

So first off, what is insulin resistance? Well, let's make this very, very simple. You have your pancreas and inside your pancreas you have these little beta cells, okay? When you consume carbohydrates, these carbohydrates come in and they trigger the beta cells to produce insulin, okay?

So insulin is then released and normally insulin goes to a cell and tells the cell to open up so that the carbohydrates can get into the cell. Well, insulin resistance means that your cell has a little wall in front of it and it can't let insulin and carbohydrates in.

It's insulin resistant. So you see the insulin just kind of bounces off the cell. So basically what happens is the cell has gotten so used to seeing insulin all the time from, of course, blood glucose coming in so much that it ends up just shutting the door to it. It's like developing the habituation of a fan being on for a long time. It just becomes white noise after a while. So it can be very dangerous stuff.

So the first one is what's known as Acanthosis. Okay. Now what this is, is high levels of insulin in, and basically the body's trying to produce a lot of insulin, it causes the skin cells to reproduce really rapidly and also increases melanin. So what ends up happening is you get this almost blotchiness to the skin, but more so you get like a redness and a darkness. So you've noticed that, well, I'm not really tan, but I look kind of reddish dark.

Well that could be a sign, okay? Because the skin cells reproduce rapidly. So you really end up developing this acanthosis. So that's a hard sign to really diagnose because you really have to know what you're looking for. But when it's coupled with some of these other things is when it adds up.

Okay, the next up is going to be tingling. This is one that I suffered with and didn't really realize. In fact, I thought it was just the fact that I was overweight and my muscles were fatigued.

Okay? So excess glucose ultimately ends up damaging the nerves and the extremities. So then what's happening is your brain is having a hard time sending the signal, and when it does send the signal, it gets disrupted and it gives you that kind of pins and needles feeling.

Okay, here's an interesting one. You're hungry after eating, you eat, you're satiated, you're full for a minute, and then you get hungry again and you start thinking that, "Well, maybe it's just the blood sugar just rising and falling." Now it's a little bit more complicated than that.

You see, what's happening is your glucose is not getting into the cell because the insulin is not working, right, it's not letting the glucose in. So what's happening is the cell is never getting a true signal that it's been nourished.

So your cells throughout your body are just waiting for glucose to come in, but the glucose isn't coming in. So the cells are telling your brain that they're hungry still. So it's sending mixed signals to your brain, telling you to eat more when in reality you're just packing on calories and packing on pounds because what's happening is your cells aren't actually getting nourished.



Nicholas Norwitz - Oxford Ketone PhD Researcher and Harvard Med Student:

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