Meningococcal infection: Complement deficiency associated to Meningococcal infection

Key Concepts related to complement deficiency.

1. Complement deficiency of C5, C6 C8, C9 and Properdin are highly associated to Meningitis, mainly caused by Neisseria meningitidis
2. Tetravalent meningococcal vaccine is used as prophylactic therapy in patients with above deficiencies.

Content

00:22 - CNS infection
01:16 - Meningitis characteristics
01:55 - Meningitis common symptoms
03:23 - Meningitis lab diagnosis
- 04:06 - Meningitis common causes
- 04:39 - CSF finding differentials
- 06:02 - CSF gram staining
- 06:44 - CSF culture of bacteria
06:31 - Meningitis: defects in the complement system (Role of MAC and Properdin in meningitis
10:07 - Thank you

Meningitis,C8 deficiency,MAC deficiency,Properdin deficiency,